Nausea/vomiting

Cause & Drug of Nausea Vomiting

Vomiting center ถูกกระตุ้นบริเวณ

• Chemoreceptor trigger zone

  • CMT, RT, Mo, digoxin, hypo K, hyper Ca, uremia

  • Tx : Ondansetron, Haloperidol, Metoclopramide (plasil)
    
    

• Abdominal visceral

  • constipation, bowel obstruction, RT, gastric stasis & irritation, cough, sputum, oral candidiasis

  • Tx : Prokinetic – Metoclopramide

  • Tx : Antisecretory – Buscopan, Ranitidine, octreotide
    
    

• Cerebral cortex

  •  IICP, hypo Na, fear & anxiety

  • Tx : dexamethasone, lorazepam

• Vestibular apparatus

  • migraine, vertigo, infection, motion sickness

  • Tx : Diphenhydramine (Diphenhydramine Benadryl ยาแก้แพ้ ลดน้ำมูก แก้ไอได้อีกด้วย #Benadryl)
    
    

Ref. Twycross R, Wilcock A, Toller CR. 2009.